HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromopentane → 4-methoxy-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1H-indole-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromopentane | HCID 8057 | — |
| Reactant | 4-Bromoindole | HCID 676494 | — |
| Reactant | 2-(Bromomethyl)-5-(trifluoromethyl)furan | HCID 2794605 | — |
| Reactant | 4-methoxy-2,3-dihydro-1H-indole-2,3-dione | HCID 11378819 | — |
| Product | 4-methoxy-1-{[5-(trifluoromethyl)-2-furyl]methyl}-1H-indole-2,3-dione | HCID 66642695 | — |
Reaction Steps
Following the procedure as described in PREPARATION 1A, and making non-critical variations to replace 4-bromoindole with 4-methoxy-1H-indole-2,3-dione, and 1-bromopentane with 2-(bromomethyl)-5-(trifluoromethyl)furan, the title compound was obtained (26%): MS (ES+) m/z 348.2 (M+23).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466188B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-15fba71e55c046ff8daa1edaef6e8460 |
| Source note | uspto-grants-2013_06 |