HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxybenzotriazole → HCID 178522633, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | HOAt | HCID 181649 | — |
| Reactant | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 178524625 | HCID 178524625 | — |
| Product | HCID 178522633 | HCID 178522633 | — |
Reaction Steps
The title compound was synthesized according to the synthesis method of a compound Ia-46 described later using 2-hydroxy-4-quinolinecarboxylic acid, commercially available amine, HBTU, and HOBt instead of 2-(4-fluorophenyl)-4-quinolinecarboxylic acid, HATU, and HOAt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466290B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-98256e3ef7264c76951ee9f7f832af0e |
| Source note | uspto-grants-2013_06 |