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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1259849Generated: October 30, 2026

1-Hydroxybenzotriazole → HCID 67205075, compound

https://huagongshe.com/reaction/1259849

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantHOAtHCID 181649—
ReactantMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
ReactantMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
ReactantHCID 15814118HCID 15814118—
ProductHCID 67205075HCID 67205075—

Reaction Steps

The title compound was synthesized according to the synthesis method of a compound Ia-46 described later using 2-(2-nitrophenyl)-4-quinolinecarboxylic acid described in Reference Example 7, HBTU, and HOBt instead of 2-(4-fluorophenyl)-4-quinolinecarboxylic acid, HATU, and HOAt, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08466290B2
Source datasetuspto-grants-2013_06
ORD IDord-abe88a4796274fc58fae3752ca0ade00
Source noteuspto-grants-2013_06