HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxybenzotriazole → HCID 67204213, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | HOAt | HCID 181649 | — |
| Reactant | 6-Fluoro-2-phenylquinoline-4-carboxylic acid | HCID 763956 | — |
| Reactant | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Product | HCID 67204213 | HCID 67204213 | — |
Reaction Steps
The title compound was synthesized according to the synthesis method of the compound Ia-46 using 6-fluoro-2-phenyl-4-quinolinecarboxylic acid described in Reference Example 17, HBTU, and HOBt instead of 2-(4-fluorophenyl)-4-quinolinecarboxylic acid, HATU, and HOAt, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466290B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-bccc1231043b40b19d08d05ebad449d2 |
| Source note | uspto-grants-2013_06 |