Acetone → 7-[2-(4-acetylpiperazin-1-yl)ethoxy]-4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinazoline
Reaction equation
[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][O:12][c:13]2[c:14]([O:24][CH3:25])[cH:15][c:16]3[c:17]([Cl:23])[n:18][cH:19][n:20][c:21]3[cH:22]2)[CH2:8][CH2:9]1.[C:38](=[O:39])([O-:40])[O-:41].[CH3:44][N:45]([CH3:46])[C:47](=[O:48])[CH3:49].[CH3:50][C:51](=[O:52])[CH3:53].[F:26][c:27]1[c:28]2[cH:29][c:30]([CH3:37])[nH:31][c:32]2[cH:33][cH:34][c:35]1[OH:36].[K+:42].[K+:43]>>[C:1]([CH3:2])(=[O:3])[N:4]1[CH2:5][CH2:6][N:7]([CH2:10][CH2:11][O:12][c:13]2[c:14]([O:24][CH3:25])[cH:15][c:16]3[c:17]([O:36][c:35]4[c:27]([F:26])[c:28]5[cH:29][c:30]([CH3:37])[nH:31][c:32]5[cH:33][cH:34]4)[n:18][cH:19][n:20][c:21]3[cH:22]2)[CH2:8][CH2:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a01219c4d60349a095c91d75af21a031
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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