Triethylamine → 2,4,6-Triiodophenyl penta-4-enoate

HRID 1260119Notes

Reaction equation

HRID 1260119 reaction equation
[CH:1]1[C:2]([I:10])=[CH:3][C:4]([I:9])=[C:5]([OH:8])[C:6]=1[I:7].[C:11](Cl)(=[O:16])[CH:12]=[CH:13][CH2:14][CH3:15].C(N(CC)CC)C>ClCCl>[C:11]([O:8][C:5]1[C:6]([I:7])=[CH:1][C:2]([I:10])=[CH:3][C:4]=1[I:9])(=[O:16])[CH2:12][CH2:13][CH:14]=[CH2:15]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 118622,4,6-TriiodophenolHCID 2760310HCID 2760310, compound

Product 1

HCID 668959352,4,6-Triiodophenyl penta-4-enoate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

First, 9 g of triiodophenol was dissolved in 150 mL dichloromethane under argon. Then, 3.15 mL of pentenoyl chloride was added while stirring. Triethylamine was then added slowly and stirred for 4 hr. The solution was washed with 100 mL of water and evaporated to dryness, leaving 2,4,6-triiodophenyl penta-4-enoate.

Workup

  1. stirringstirred for 4 hr
  2. washThe solution was washed with 100 mL of water
  3. customevaporated to dryness

Sources & evidence

ORD record
ord-f5ec7c7b42c14d5aadebb227c5c52ac9
Source dataset
uspto-grants-2013_06
Patent number
US08470035B2

Reaction notes

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