Methanol → HCID 178448096, compound

Participants

Reaction Steps

KMUP-1 (8.0 g) is dissolved in a mixture of ethanol (100 mL) and water (30 mL), to which nateglinide (9.1 g) dissolved in ethyl alcohol (150 mL) is added, and the mixture is reacted at 50° C. for 20 mins. After cooling the mixture, the white precipitate is obtained, to which the methanol is added under room temperature and being incubated over night for re-crystallization. After filtering, KMUP-1-nateglinide complex (15.3 g) is obtained.

Provenance & Evidence