Hydrochloric Acid → 1-(2-fluorophenyl)-1H-pyrazol-3-amine

HRID 1260312Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][NH2:9].Cl>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH:7]=[CH:2][C:3]([NH2:8])=[N:9]1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 4238442-Fluorophenylhydrazine hydrochloride

Product 1

HCID 99908071-(2-fluorophenyl)-1H-pyrazol-3-amineYield 24%

Procedure

According to the method described in step 1 of example 2, the amine was obtained starting from 2-fluorophenylhydrazine×HCl as brown solid in 24% yield.

Sources & evidence

ORD record: ord-439a3ce6db234184afecaba15ae8997f
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08470820B2

Reaction notes

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