Pyridine, 2-(4-nitro-1H-imidazol-1-yl)- → HCID 66520792, compound

Participants

Reaction Steps

To a solution of 2-(4-nitro-imidazol-1-yl)-pyridine (150 mg, 0.79 mmol) in THF (12 ml) was added under inert gas atmosphere 10% Pd/C (28 mg, 0.026 mmol). Upon evacuation, the reaction vessel was charged with hydrogen and the reaction mixture was stirred at ambient temperature overnight. The catalyst was filtered off, the solvent volume was reduced and the amine was used without any further purification as ˜0.2 M THF solution for the next step.

Provenance & Evidence