HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86761883, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-tert-Butoxycarbonylaminopropyl methanesulfonate | HCID 14427184 | — |
| Reactant | HCID 67071691 | HCID 67071691 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86761883 | HCID 86761883 | — |
Reaction Steps
4-(5-Isopropoxypyridin-2-yloxy)phenol (592 mg, 2.41 mmol) and 2-tert-butoxycarbonylaminopropyl methanesulfonate (734 mg, 2.89 mmol) were reacted with sodium hydride in DMF in analogy to example 2c. Yield: 414 mg (43%), M+H+: 403.19.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470841B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-e154427bf5a8411dbb1a0061007a946e |
| Source note | uspto-grants-2013_06 |