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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260643Generated: October 30, 2026

4-Fluoro-2-(trifluoromethyl)benzaldehyde → 2-(Bromomethyl)-5-(methylsulphonyl)benzotrifluoride

https://huagongshe.com/reaction/1260643

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-(trifluoromethyl)benzaldehydeHCID 522940—
Reactant1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzeneHCID 2761083—
Product2-(Bromomethyl)-5-(methylsulphonyl)benzotrifluorideHCID 51342049—

Reaction Steps

The titled compound is prepared analogously to 1-bromomethyl-2-chloro-4-methanesulfonyl-benzene by replacing 2-chloro-4-fluorobenzaldehyde (step 90a) with 4-fluoro-2-trifluoromethylbenzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470848B2
Source datasetuspto-grants-2013_06
ORD IDord-01caf164b4df4a1883ba3a48cc5aca67
Source noteuspto-grants-2013_06