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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260735Generated: November 1, 2026

3,3,3-Trifluoropropionic acid → HCID 178520719, compound

https://huagongshe.com/reaction/1260735

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3,3-Trifluoropropionic acidHCID 2777972—
ReactantHCID 178478590HCID 178478590—
ProductHCID 178520719HCID 178520719—

Reaction Steps

The title compound, white solid (49 mg, 70%), MS (ISP) m/z=441.4 [(M+H)+], mp 216.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (70.4 mg, 0.16 mmol) 3,3,3-trifluoropropanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470828B2
Source datasetuspto-grants-2013_06
ORD IDord-4220f30c342a4e0c8056f600f07c2e67
Source noteuspto-grants-2013_06