HCID 2779071, compound → HCID 178520778, compound

Participants

Reaction Steps

The title compound, white solid (133 mg, 94%), MS (ISP) m/z=471.5 [(M+H)+], mp 214.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and (R)-4,4,4-trifluoro-3-hydroxybutanoic acid.

Provenance & Evidence