4-(Trifluoromethyl)benzoic acid → HCID 178523726, compound

Participants

Reaction Steps

The title compound, white solid (117 mg, 93%), MS (ISP) m/z=503.3 [(M+H)+], mp 242.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 4-trifluoromethyl-benzoic acid.

Provenance & Evidence