2-Hydroxyisobutyric acid → HCID 178459882, compound

Participants

Reaction Steps

The title compound, white solid (92 mg, 88%), MS (ISP) m/z=417.5 [(M+H)+], mp 241° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 2-hydroxy-2-methyl-propionic acid.

Provenance & Evidence