Methyl 3,3-dimethoxypropionate → HCID 178495584, compound

Participants

Reaction Steps

The title compound, white solid (103 mg, 92%), MS (ISP) m/z=447.4 [(M+H)+], mp 218° C., was prepared in accordance with the general method of example 5 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and methyl 3,3-dimethoxy-propanoate.

Provenance & Evidence