Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260770Generated: November 1, 2026

(1,1'-Biphenyl)-4-carboxylic acid → HCID 178523723, compound

https://huagongshe.com/reaction/1260770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReactantHCID 178478590HCID 178478590—
ProductHCID 178523723HCID 178523723—

Reaction Steps

The title compound, white solid (117 mg, 92%), MS (ISP) m/z=511.6 [(M+H)+], mp 220.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and biphenyl-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470828B2
Source datasetuspto-grants-2013_06
ORD IDord-360b6eb8cfd64bae9fdf515d3ca08003
Source noteuspto-grants-2013_06