1-Hydroxycyclobutanecarboxylic acid → HCID 178523742, compound

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Reaction Steps

The title compound, off-white solid (68 mg, 64%), MS (ISP) m/z=429.4 [(M+H)+], mp 250° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 1-hydroxy-cyclobutane-carboxylic acid.

Provenance & Evidence