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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260883Generated: October 30, 2026

3-Fluoro-4-methylbenzyl bromide → 5-Chloro-1-(3-fluoro-4-methylbenzyl)-2-imino-1,2-dihydropyridine-3-carboxamide hydrobromide

https://huagongshe.com/reaction/1260883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-methylbenzyl bromideHCID 2774603—
Reactant2-Amino-5-chloronicotinamideHCID 66876883—
Product5-Chloro-1-(3-fluoro-4-methylbenzyl)-2-imino-1,2-dihydropyridine-3-carboxamide hydrobromideHCID 68661492—

Reaction Steps

According to the method of Example 172, 2-amino-5-chloronicotinamide was reacted with 4-(bromomethyl)-2-fluoro-1-methylbenzene to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470859B2
Source datasetuspto-grants-2013_06
ORD IDord-39ac05bee61940be9e2f64a107623f58
Source noteuspto-grants-2013_06