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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260888Generated: October 26, 2026

(3-Morpholinophenyl)methylamine → 5-Chloro-2-imino-1-(3-morpholin-4-ylbenzyl)-1,2-dihydropyridine-3-carboxamide hydrochloride

https://huagongshe.com/reaction/1260888

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Morpholinophenyl)methylamineHCID 2795550—
Reactant2-Amino-5-chloronicotinamideHCID 66876883—
Product5-Chloro-2-imino-1-(3-morpholin-4-ylbenzyl)-1,2-dihydropyridine-3-carboxamide hydrochlorideHCID 68662392—

Reaction Steps

According to the method of Example 179, 2-amino-5-chloronicotinamide was reacted with 1-(3-morpholin-4-ylphenyl)methanamine to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470859B2
Source datasetuspto-grants-2013_06
ORD IDord-d773e3a66e84488c8c664269e8112eca
Source noteuspto-grants-2013_06