4-Chlorobenzoic Acid → HCID 86631284, compound

HRID 1260918Notes

Reaction equation

HRID 1260918 reaction equation
C1(C)C=CC(S(O)(=O)=O)=CC=1.[NH2:12][C@@H:13]1[CH2:18][CH2:17][N:16]([C:19]([O:21][C:22]([CH3:25])([CH3:24])[CH3:23])=[O:20])[CH2:15][C@H:14]1[C:26]1[CH:31]=[CH:30][C:29]([F:32])=[C:28]([Cl:33])[CH:27]=1.[Cl:34][C:35]1[CH:43]=[CH:42][C:38]([C:39](O)=[O:40])=[CH:37][CH:36]=1>>[Cl:33][C:28]1[CH:27]=[C:26]([C@H:14]2[C@H:13]([NH:12][C:39]([C:38]3[CH:42]=[CH:43][C:35]([Cl:34])=[CH:36][CH:37]=3)=[O:40])[CH2:18][CH2:17][N:16]([C:19]([O:21][C:22]([CH3:25])([CH3:23])[CH3:24])=[O:20])[CH2:15]2)[CH:31]=[CH:30][C:29]=1[F:32]

Participants

3

Reactant 2

HCID 63184-Chlorobenzoic AcidHCID 86631285HCID 86631285, compound

Product 1

HCID 86631284HCID 86631284, compound

Procedure

sing the compound obtained in step 1 and 4-chlorobenzoic acid, and by the reaction and purification in the same manner as in Reference Example 1, step 5, the title compound was obtained.

Workup

  1. customby the reaction and purification in the same manner as in Reference Example 1, step 5

Sources & evidence

ORD record
ord-1b26835a7dca40bda6e7d13d82dd0052
Source dataset
uspto-grants-2013_06
Patent number
US08470816B2

Reaction notes

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