(3R,4R)-1-[(1-acetylpiperidin-4-yl)carbonyl]-3-(3,4-dichlorophenyl)-N-methylpiperidin-4-amine → N-[(3R,4R)-1-[(1-acetylpiperidin-4-yl)carbonyl]-3-(3,4-dichlorophenyl)piperidin-4-yl]-6-methoxy-N,1-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-7-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	(3R,4R)-1-[(1-acetylpiperidin-4-yl)carbonyl]-3-(3,4-dichlorophenyl)-N-methylpiperidin-4-amine	HCID 57741761	—
Reactant	6-Methoxy-1-methyl-2-oxo-1,2,3,4-tetrahydroquinoline-7-carboxylic acid	HCID 68935618	—
Product	N-[(3R,4R)-1-[(1-acetylpiperidin-4-yl)carbonyl]-3-(3,4-dichlorophenyl)piperidin-4-yl]-6-methoxy-N,1-dimethyl-2-oxo-1,2,3,4-tetrahydroquinoline-7-carboxamide	HCID 68933811	—

Reaction Steps

Using the compound obtained in step 1 and the compound obtained in Example 78, and by the reaction and purification in the same manner as in Example 3, the title compound was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08470816B2
Source dataset	uspto-grants-2013_06
ORD ID	ord-a863c599924d4c0b9757272343909be9
Source note	uspto-grants-2013_06