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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1260996생성일: 2026년 10월 27일

1-(Cyclopropylcarbonyl)piperidine-4-carboxylic acid → 4-bromo-N-[(3R,4R)-1-{[1-(cyclopropylcarbonyl)piperidin-4-yl]carbonyl}-3-(3,4-dichlorophenyl)piperidin-4-yl]-N-methylbenzamide

https://huagongshe.com/reaction/1260996

반응식

참여 물질

역할이름HCID투입량
반응물1-(Cyclopropylcarbonyl)piperidine-4-carboxylic acidHCID 8902915—
반응물4-bromo-N-[(3R,4R)-3-(3,4-dichlorophenyl)piperidin-4-yl]-N-methylbenzamideHCID 68930105—
생성물4-bromo-N-[(3R,4R)-1-{[1-(cyclopropylcarbonyl)piperidin-4-yl]carbonyl}-3-(3,4-dichlorophenyl)piperidin-4-yl]-N-methylbenzamideHCID 68872668—

반응 단계

Using the compound obtained in Example 633, step 3 and 1-(cyclopropylcarbonyl)piperidine-4-carboxylic acid, and by the reaction and purification in the same manner as in Example 97, the title compound was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08470816B2
출처 데이터셋uspto-grants-2013_06
ORD IDord-d8ef719a9da54748b36d737c5c326f56
출처 메모uspto-grants-2013_06