7-chloro-2-(1-methyl-1H-imidazol-2-yl)-thieno[3,2-b]pyridine → 7-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridine

Participants

Role	Name	HCID	Charge
Reactant	7-chloro-2-(1-methyl-1H-imidazol-2-yl)-thieno[3,2-b]pyridine	HCID 22143563	—
Reactant	7-(2-Fluoro-4-nitrophenoxy)-2-(thiazol-2-yl)thieno[3,2-b]pyridine	HCID 59424425	—
Product	7-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridine	HCID 59424518	45%

Reaction Steps

Starting from compound 214 (scheme 46) and following the procedure described above for the synthesis of compound 11 (scheme 2, step 3, example 12), title compound 218 was obtained in 45% yield. MS (m/z) 371.1 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08470850B2
Source dataset	uspto-grants-2013_06
ORD ID	ord-b4c61faca9714b36882d60266ec09998
Source note	uspto-grants-2013_06