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HRID1261816

反应详情

EQUATION

反应方程式

HRID 1261816 的结构方程式

REACTANTS

反应物

2
结构：CCCC[N+](CCCC)(CCCC)CCCC.[F-]
HCID2724141

Tetra-n-butylammonium fluoride

C16H36FN

结构：COC(OC)[C@@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CC(O)O1
HCID69184843

未命名化合物

PRODUCTS

生成物

1
结构：COC(OC)[C@@H]1C[C@@H](O)CC(O)O1
HCID25050459

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

2 次

CONDITIONS

反应条件

温度
25 °C

PROCEDURE

实验过程

To a solution of 0.47 g of (4R,6S)-4-(tert-butyldimethylsilyloxy)-6-(dimethoxymethyl)-tetrahydro-2H-pyran-2-ol (I′) in 14 mL of tetrahydrofurane, tetra-n-butylammonium fluoride in 14 mL of THF is added. After 15 minutes of stirring at 25° C., the THF is distilled off. The residue is flash chromatographed (methanol). After methanol is distilled off, the title compound is obtained as an oil.

WORKUP

后处理

  1. distillationthe THF is distilled off
  2. customchromatographed (methanol)
  3. distillationAfter methanol is distilled off