Dichloromethane → 4-[(7-chloro-4-methyl-1H-indol-5-yl)amino]-5-[5-(piperazin-1-ylmethyl)-1-benzofuran-2-yl]nicotinonitrile
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([NH:12][c:13]2[c:14](-[c:21]3[o:22][c:23]4[c:24]([cH:25]3)[cH:26][c:27]([CH2:30][N:31]3[CH2:32][CH2:33][N:34]([C:37]([O:38][C:39]([CH3:40])([CH3:41])[CH3:42])=[O:43])[CH2:35][CH2:36]3)[cH:28][cH:29]4)[cH:15][n:16][cH:17][c:18]2[C:19]#[N:20])[c:5]([CH3:11])[c:6]2[cH:7][cH:8][nH:9][c:10]12.[Cl:44][CH2:45][Cl:46].[OH:47][C:48]([C:49]([F:50])([F:51])[F:52])=[O:53]>>[Cl:1][c:2]1[cH:3][c:4]([NH:12][c:13]2[c:14](-[c:21]3[o:22][c:23]4[c:24]([cH:25]3)[cH:26][c:27]([CH2:30][N:31]3[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]3)[cH:28][cH:29]4)[cH:15][n:16][cH:17][c:18]2[C:19]#[N:20])[c:5]([CH3:11])[c:6]2[cH:7][cH:8][nH:9][c:10]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8c5379f14ff545bcaaf150f30d06917b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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