反应详情

[1-(4-Amino-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone was prepared in a similar manner as 2-Methoxy-4-(4-methyl-piperazin-1-yl)-phenylamine of Example 33 after substituting (4-Methyl-piperazin-1-yl)-[1-(4-nitro-phenyl)-piperidin-3-yl]-methanone for 1-(3-Methoxy-4-nitro-phenyl)-4-methyl-piperazine, and using EtOH as the solvent rather than MeOH (75 mg, 99%). LC/MS (E/I+) 303.19 (M+H).