HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-1-(3-Methoxy-4-nitro-phenyl)-piperidine-3-carboxylic acid → HCID 66711060, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-1-(3-Methoxy-4-nitro-phenyl)-piperidine-3-carboxylic acid | HCID 66711822 | — |
| Reactant | [(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone | HCID 66711868 | — |
| Product | HCID 66711060 | HCID 66711060 | — |
Reaction Steps
[(R)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone was prepared in an analogous fashion to) [(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone of Example 460b replacing (S)-1-(3-Methoxy-4-nitro-phenyl)-piperidine-3-carboxylic acid with (R)-1-(3-Methoxy-4-nitro-phenyl)-piperidine-3-carboxylic acid. [(R)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone was isolated as a yellow oil after described extractive workup and was used without further manipulation. LC: 88% pure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08471005B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-bb669547fe054709bd8650d9edb37681 |
| Source note | uspto-grants-2013_06 |