4-(4-Methoxy-3-nitrobenzoyl)morpholine → 2-Methoxy-5-(morpholine-4-carbonyl)aniline

Participants

Reaction Steps

(3-Amino-4-methoxy-phenyl)-morpholin-4-yl-methanone was prepared in an analogous fashion to [(S)-1-(4-Amino-3-methoxy-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone of Example 460c replacing [(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone with (4-Methoxy-3-nitro-phenyl)-morpholin-4-yl-methanone. LC/MS (E/I+) 237.05 (M+H).

Provenance & Evidence