HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-5-(morpholine-4-carbonyl)aniline → 2-Methoxy-5-morpholin-4-ylmethyl-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-5-(morpholine-4-carbonyl)aniline | HCID 16770478 | — |
| Reactant | 2-Methoxy-5-((4-methylpiperazin-1-yl)methyl)aniline | HCID 29301207 | — |
| Product | 2-Methoxy-5-morpholin-4-ylmethyl-phenylamine | HCID 29559524 | — |
Reaction Steps
2-Methoxy-5-morpholin-4-ylmethyl-phenylamine was prepared in an analogous fashion to 2-Methoxy-5-(4-methyl-piperazin-1-ylmethyl)-phenylamine of Example 495a replacing (3-Amino-4-methoxy-phenyl)-(4-methyl-piperazin-1-yl)-methanone with (3-Amino-4-methoxy-phenyl)-morpholin-4-yl-methanone (1.31 g, 73%). LC/MS (E/I+) 223.05 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08471005B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-7ed3001f4a6b4a51968b7fecc31333e3 |
| Source note | uspto-grants-2013_06 |