HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[(3-Methoxy-4-nitrophenyl)methyl]-2-methyl-1H-imidazole → 2-Methoxy-4-[(2-methyl-1H-imidazol-1-yl)methyl]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[(3-Methoxy-4-nitrophenyl)methyl]-2-methyl-1H-imidazole | HCID 57416137 | — |
| Reactant | HCID 66711468 | HCID 66711468 | — |
| Product | 2-Methoxy-4-[(2-methyl-1H-imidazol-1-yl)methyl]aniline | HCID 57416077 | — |
Reaction Steps
2-Methoxy-4-(2-methyl-imidazol-1-ylmethyl)-phenylamine was prepared in an analogous fashion to [(S)-1-(4-Amino-3-methoxy-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone of Example 460c replacing [(S)-1-(3-Methoxy-4-nitro-phenyl)-piperidin-3-yl]-(4-methyl-piperazin-1-yl)-methanone with 1-(3-Methoxy-4-nitro-benzyl)-2-methyl-1H-imidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08471005B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-86d46f92badc44559114930efe21e2a2 |
| Source note | uspto-grants-2013_06 |