HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 4-(Ethoxycarbonyl)furan-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 3,4-Diethyl 3,4-furandicarboxylate | HCID 35399 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(Ethoxycarbonyl)furan-3-carboxylic acid | HCID 271570 | — |
Reaction Steps
A solution of 235 gm of furan-3,4-dicarboxylic acid diethyl ester and 62.1 gm of potassium hydroxide in 800 ml of 60% ethanol was stirred for 2 hours at room temperature, and then the solvent was distilled off in vacuo. The residue was acidified by carefully adding an aqueous KHSO4 solution dropwise thereto, while stirring, and the monoester was extracted with methylene chloride and crystallized from ethyl acetate/petroleum ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04452789 |
| Source dataset | uspto-grants-1984_06 |
| ORD ID | ord-e5ac6c5600514fe0afecdff490d05b55 |
| Source note | uspto-grants-1984_06 |