Ethyl isocyanate → HCID 13320288, compound

HRID 1262613Notes

Reaction equation

HRID 1262613 reaction equation
[CH2:1]([C:4]1[CH:18]=[CH:17][CH:16]=[CH:15][C:5]=1[O:6][C@@H:7]1[CH2:11][N:10]([CH2:12][CH3:13])[CH2:9][C@H:8]1[OH:14])[CH:2]=[CH2:3].[CH2:19]([N:21]=[C:22]=[O:23])[CH3:20]>C1C=CC=CC=1>[CH2:19]([NH:21][C:22]([O:14][C@H:8]1[C@H:7]([O:6][C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]=2[CH2:1][CH:2]=[CH2:3])[CH2:11][N:10]([CH2:12][CH3:13])[CH2:9]1)=[O:23])[CH3:20]

Participants

4

Reactant 2

HCID 8022Ethyl isocyanateHCID 13320286HCID 13320286, compound

Product 1

HCID 13320288HCID 13320288, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

A mixture of 7.3 g. of trans 4-(2-allylphenoxy)-1-ethyl-3-pyrrolidinol and 2.5 g. of ethylisocyanate in 30 ml. of benzene was stirred for 48 hr. The benzene was replaced by petroleum ether and the solution chilled. The yield of precipitate melting at 53-6° C. was 78%.

Workup

  1. additionA mixture of 7.3 g
  2. temperaturethe solution chilled

Sources & evidence

ORD record
ord-3e31cf70295f4c80bba160b667277565
Source dataset
uspto-grants-1984_06
Patent number
US04452809

Reaction notes

Loading…