Methyl vinyl ketone → HCID 20456182, compound

HRID 1262820Notes

Reaction equation

HRID 1262820 reaction equation
[CH2:1]([N:5]1[C:14](=[S:15])[C:13]2[NH:12][CH:11]=[N:10][C:9]=2[N:8]([CH2:16][CH2:17][CH2:18][CH3:19])[C:6]1=[O:7])[CH2:2][CH2:3][CH3:4].[CH3:20][C:21]([CH:23]=[CH2:24])=[O:22].C(N(CC)CC)C>C(O)C>[CH2:1]([N:5]1[C:14](=[S:15])[C:13]2[N:12]([CH2:24][CH2:23][C:21](=[O:22])[CH3:20])[CH:11]=[N:10][C:9]=2[N:8]([CH2:16][CH2:17][CH2:18][CH3:19])[C:6]1=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 6570Methyl vinyl ketoneHCID 8471TriethylamineHCID 20456185HCID 20456185, compound

Product 1

HCID 20456182HCID 20456182, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1,3-di-n-butyl-6-thioxanthine (8,3 g), methylvinylketone (2,9 ml) and triethylamine (1 ml) were dissolved in ethanol (10 ml) and the mixture was slowly heated with stirring at 40°-50° C. for one hour. After cooling of the clear solution, the 1,3-di-n-butyl-7-(3-oxobutyl)-6-thioxanthine precipitated in the form of yellow needles.

Workup

  1. temperaturethe mixture was slowly heated
  2. temperatureAfter cooling of the clear solution
  3. customthe 1,3-di-n-butyl-7-(3-oxobutyl)-6-thioxanthine precipitated in the form of yellow needles

Sources & evidence

ORD record
ord-812482061dd6469a926d4c91da98201c
Source dataset
uspto-grants-1984_06
Patent number
US04454138

Reaction notes

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