1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 13320091, compound

HRID 1262870Notes

Reaction equation

HRID 1262870 reaction equation
[Br:1][CH:2]([Br:23])[C:3](Br)([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:4][N:5]1[C:9](=[O:10])[C:8]2=[CH:11][CH:12]=[CH:13][CH:14]=[C:7]2[C:6]1=[O:15].C1CCN2C(=NCCC2)CC1>CS(C)=O>[Br:23][C:2]([Br:1])=[C:3]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:4][N:5]1[C:9](=[O:10])[C:8]2=[CH:11][CH:12]=[CH:13][CH:14]=[C:7]2[C:6]1=[O:15]

Participants

4

Reactant 2

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 13320154HCID 13320154, compound

Product 1

HCID 13320091HCID 13320091, compoundYield 69.4%

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

A solution of 1,1,2-tribromo-2-phenyl-3-phthalimidopropane (1.22 g) and DBU (0.50 g) in DMSO (50 ml) is heated at 85° for 4 hours. Work-up as described in Example 19 C gives 1,1-dibromo-2-phenyl-3-phthalimidopropene (0.71 g): colorless needles; m.p. 154°-155°;

Sources & evidence

ORD record
ord-76fd3574415146939837dcd6a337d648
Source dataset
uspto-grants-1984_06
Patent number
US04454158

Reaction notes

Loading…