HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,3-Dimethylbutanoyl chloride → 8-Bromo-1-(2,2-dimethylpropyl)-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,3-Dimethylbutanoyl chloride | HCID 81514 | — |
| Edukt | 7-bromo-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine | HCID 12570862 | — |
| Produkt | 8-Bromo-1-(2,2-dimethylpropyl)-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine | HCID 13343346 | — |
Reaktionsschritte
Following the procedure of Example 5, 2.0 g of 7-bromo-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine is reacted with 1.01 ml of tert-butyl acetylchloride to yield 1.17 g of title product with melting point 229.5°-232° C. and 0.30 g of title product with melting point 205°-219° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04455307 |
| Quelldatensatz | uspto-grants-1984_06 |
| ORD ID | ord-c75af68d90a04b4d869e5131bcde41fa |
| Quellennotiz | uspto-grants-1984_06 |