Potassium Carbonate → HCID 20256663, compound

HRID 1263199Notes

Reaction equation

HRID 1263199 reaction equation
[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[C:7]([N+]([O-])=O)[CH:6]=1.[OH:25][CH:26]([P:28](=[O:33])([O:31][CH3:32])[O:29][CH3:30])[CH3:27].C(=O)([O-])[O-].[K+].[K+]>CC(=O)CC>[N+:11]([C:8]1[CH:9]=[CH:10][C:5]([O:4][C:3]2[CH:17]=[CH:18][C:19]([C:21]([F:24])([F:23])[F:22])=[CH:20][C:2]=2[Cl:1])=[CH:6][C:7]=1[O:25][CH:26]([P:28](=[O:33])([O:31][CH3:32])[O:29][CH3:30])[CH3:27])([O-:13])=[O:12]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 112018Dimethyl (1-hydroxyethyl)phosphonateHCID 156238Benzene, 2-chloro-1-(3,4-dinitrophenoxy)-4-(trifluoromethyl)-

Product 1

HCID 20256663HCID 20256663, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

A mixture of 4-(2-chloro-4-trifluoromethylphenoxy)-1,2-dinitrobenzene (600 mg), dimethyl α-hydroxyethylphosphonate (382 mg), potassium carbonate (343 mg) and 2-butanone (8 ml) is heated under reflux for 24 hours. The reaction mixture is filtered, and the filtrate is concentrated and purified by prep. TLC to give dimethyl α-[2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)phenoxy]ethylphosphonate.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 24 hours
  3. filtrationThe reaction mixture is filtered
  4. concentrationthe filtrate is concentrated
  5. custompurified by prep

Sources & evidence

ORD record
ord-c19029303c414599a1d42014ad57673f
Source dataset
uspto-grants-1984_06
Patent number
US04456464

Reaction notes

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