HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphoric Acid → 4-methylbenzothiazole-5-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphoric Acid | HCID 1004 | — |
| Reactant | Methyl 4-Methylbenzothiazole-5-carboxylate | HCID 18616057 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | 4-methylbenzothiazole-5-carboxylic Acid | HCID 11480970 | — |
Reaction Steps
16.6 g of methyl 4-methylbenzothiazole-5-carboxylate (0.08 mol) were dissolved in 280 ml of 5% strength aqueous potassium hydroxide solution and heated at reflux for 2.5 h. After cooling, the mixture was acidified using phosphoric acid. The product was filtered off and subsequently dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06541423B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-9661301a5c1d4a79a1f6f2a60ed9e312 |
| Source note | uspto-grants-2003_04 |