Hydrochloric Acid → HCID 18616050, compound

Participants

Reaction Steps

5 g of methyl 2-amino-4-methylbenzothiazole-5-carboxylate (0.02 mol) in 28.6 g of 50% strength KOH were stirred at 120° C. for 4 h. The mixture was then neutralized with 10% strength HCl and admixed with an excess of 40% strength NaNO2 solution at 0-10° C. The reaction mixture was acidified and extracted with ethyl acetate. The extract was washed and dried, and the product was obtained by stripping off the solvent. Yield: 1.3 g (28%).

Provenance & Evidence