Tetrahydrofuran → HCID 54116790, compound

HRID 1263447Notes

Reaction equation

HRID 1263447 reaction equation
O[C:2]1[C:7]2[C:8](=[O:12])O[IH](=O)[C:6]=2[CH:5]=[CH:4][CH:3]=1.[O:13]1[CH2:17][CH2:16][CH2:15][CH2:14]1>>[CH2:8]([O:12][C:14]1[CH:4]=[CH:3][CH:2]=[CH:7][C:15]=1[CH2:16][CH:17]=[O:13])[C:7]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 178519223HCID 178519223, compound

Product 1

HCID 54116790HCID 54116790, compound

Procedure

0.104 mol of hydroxy-1-oxo-benzo[d][1,2]iodoxol-3-one is added to 0.08 mol of [2-(2-benzyloxy)phenyl]ethanol in 500 ml of tetrahydrofuran. The reaction mixture is heated at reflux for 2 hours and then cooled. The precipitate is filtered off and the filtrate is evaporated.

Workup

  1. temperatureThe reaction mixture is heated
  2. temperatureat reflux for 2 hours
  3. temperaturecooled
  4. filtrationThe precipitate is filtered off
  5. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-e8ea4bf42aec4644b9040ea4e175cb3d
Source dataset
uspto-grants-2003_04
Patent number
US06541471B1

Reaction notes

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