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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1263614Generated: November 3, 2026

5-(3,4-Dichlorobenzyl-carbamoyl)-thiophene-2-carboxylic acid → 5(3,4-Dichlorobenzylcarbamoyl)pyridine-2-carbonylchloride

https://huagongshe.com/reaction/1263614

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3,4-Dichlorobenzyl-carbamoyl)-thiophene-2-carboxylic acidHCID 18617115—
Reactant5(3,4-Dichlorobenzylcarbamoyl)-pyridine-2-carboxylic acidHCID 18617184—
Product5(3,4-Dichlorobenzylcarbamoyl)pyridine-2-carbonylchlorideHCID 18617205—

Reaction Steps

Compound (13(b)) was treated in an analogous manner to compound (12(b)) in Example 12 to give 5(3,4-dichlorobenzylcarbamoyl)pyridine-2-carbonylchloride (13(c)) which was used crude in the next reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541491B1
Source datasetuspto-grants-2003_04
ORD IDord-52baa47682b942eabd003fbf7fca1a71
Source noteuspto-grants-2003_04