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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1264193Generated: October 27, 2026

2-Fluorotoluene → N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine

https://huagongshe.com/reaction/1264193

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorotolueneHCID 7241—
Reactant3-Methylamino-1-phenylpropanolHCID 2733989—
Solvent1,3-Dimethyl-2-imidazolidinoneHCID 6661—
ProductN-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amineHCID 6850813—

Reaction Steps

reacting an alkoxide of N-methyl-3-phenyl-3-hydroxypropylamine with 2-fluorotoluene in 1,3-dimethyl-2-imidazolidinone to give N-methyl-3-(2-methylphenoxy)-3-phenylpropylamine;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541668B1
Source datasetuspto-grants-2003_04
ORD IDord-4c981e30660241a59c3e1878c027c9d0
Source noteuspto-grants-2003_04