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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1264194Generated: October 26, 2026

2-Fluorotoluene → N,N-Dimethyl-3-phenyl-3-(o-tolyloxy)propan-1-amine

https://huagongshe.com/reaction/1264194

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorotolueneHCID 7241—
Reactant3-(Dimethylamino)-1-phenylpropan-1-olHCID 110665—
Solvent1,3-Dimethyl-2-imidazolidinoneHCID 6661—
ProductN,N-Dimethyl-3-phenyl-3-(o-tolyloxy)propan-1-amineHCID 12807420—

Reaction Steps

reacting an alkoxide of N,N-dimethyl-3-phenyl-3-hydroxypropylamine) with 2-fluorotoluene in 1,3-dimethyl-2-imidazolidinone to give N,N-dimethyl-3-(2-methylphenoxy)-3-phenylpropylamine;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541668B1
Source datasetuspto-grants-2003_04
ORD IDord-a1a1d6d3f50745cfbd88da0d427641f2
Source noteuspto-grants-2003_04