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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1264252Generated: October 26, 2026

N-Methyltaurine → 2-[(4-{4-[2-(3-Cyano-1H-indol-5-yl)-ethylcarbamoyl]-phenyl}-pyrimidin-2-yl)-methyl-amino]-ethanesulfonic acid

https://huagongshe.com/reaction/1264252

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethyltaurineHCID 7882—
ReactantN-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloropyrimidin-4-yl]benzamideHCID 18617562—
Product2-[(4-{4-[2-(3-Cyano-1H-indol-5-yl)-ethylcarbamoyl]-phenyl}-pyrimidin-2-yl)-methyl-amino]-ethanesulfonic acidHCID 54447362—

Reaction Steps

Using 2-methylamino-ethyl sulphonic acid and N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloro-pyrimidin-4-yl]-benzamide (reference example 1az) as substrates.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541505B1
Source datasetuspto-grants-2003_04
ORD IDord-511cdd9458b94501a8b4f92053fe56ca
Source noteuspto-grants-2003_04