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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1264264Generated: October 30, 2026

5-(Dimethylamino)amylamine → N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-(5-dimethylamino-pentylamino)-pyrimidin-4-yl]-benzamide

https://huagongshe.com/reaction/1264264

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Dimethylamino)amylamineHCID 3465925—
ReactantN-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloropyrimidin-4-yl]benzamideHCID 18617562—
ProductN-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-(5-dimethylamino-pentylamino)-pyrimidin-4-yl]-benzamideHCID 18617761—

Reaction Steps

Using 5-dimethylamino-pentylamine (reference example 93a) and and N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloro-pyrimidin-4-yl]-benzamide (reference example 1az) as substrates. MS (ion spray) m/z 496 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541505B1
Source datasetuspto-grants-2003_04
ORD IDord-7b45926f99244eadbdf8b83990cd807a
Source noteuspto-grants-2003_04