Isoamylamine → HCID 86585046, compound

HRID 1264392Notes

Reaction equation

HRID 1264392 reaction equation
Cl[CH2:2][C:3]1[N:7]=[CH:6][O:5][N:4]=1.[NH2:8][CH2:9][CH2:10][CH:11]([CH3:13])[CH3:12].[NH2:14][C@H:15](C(O)=O)[CH2:16][C:17]1[CH:26]=C2C(C=CC=C2)=C[CH:18]=1>C1(C)C=CC=CC=1>[CH3:12][CH:11]([CH3:13])[CH2:10][CH2:9][NH:8][CH2:2][C:3]1[N:7]=[CH:6][O:5][N:4]=1.[CH3:18][CH:17]([CH3:26])[CH2:16][CH2:15][NH:14][CH2:2][C:3]1[N:7]=[CH:6][O:5][N:4]=1

Participants

5

Reactant 3

HCID 7894IsoamylamineHCID 1859152-NaphthylalanineHCID 27357653-(Chloromethyl)-1,2,4-oxadiazole

Product 1

HCID 86585046HCID 86585046, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In analogy to the general synthesis of the amines, 3-(chloromethyl)-1,2,4-oxadiazole and 1-amino-3-methylbutane and Nal in toluene gave (3-Methyl-butyl)-[1,2,4]oxadiazol-3-ylmethyl-amine (3-Methyl-butyl)-[1,2,4] oxadiazol-3-ylmethyl-amine, MS: 170 (MH+).

Sources & evidence

ORD record
ord-ef24474beb634b4fa66a4f77d548d6d2
Source dataset
uspto-grants-2003_04
Patent number
US06541638B2

Reaction notes

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