Lithium Hydroxide → HCID 86585057, compound

HRID 1264406Notes

Reaction equation

C[O:2][C:3](=[O:30])[C@@H:4]([NH:8][C:9]([C@@H:11]1[CH2:15][C@H:14]([SH:16])[CH2:13][N:12]1[S:17]([C:20]1[CH:29]=[CH:28][C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=1)(=[O:19])=[O:18])=[O:10])[CH:5]([CH3:7])[CH3:6].[Li+].[OH-]>>[SH:16][C@@H:14]1[CH2:13][N:12]([S:17]([C:20]2[CH:29]=[CH:28][C:27]3[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=3)[CH:21]=2)(=[O:19])=[O:18])[C@H:11]([C:9]([NH:8][C@@H:4]([CH:5]([CH3:7])[CH3:6])[C:3]([OH:30])=[O:2])=[O:10])[CH2:15]1

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 86585058HCID 86585058, compound

Product 1

HCID 86585057HCID 86585057, compound

Procedure

(S)-2-[[(2S,4S)-4-Mercapto-1-(naphthalene-2-sulfonyl)-pyrrolidine-2-carbonyl]-amino]-3-methyl-butyric acid methyl ester was treated with 0.1M LiOH according to general procedure 5.2. to yield (S)-2-[[(2S,4S)-4-Mercapto-1-(naphthalene-2-sulfonyl)-pyrrolidine-2-carbonyl]-amino]-3-methyl-butyric acid as white foam, MS: 437 (MH+).

Sources & evidence

ORD record: ord-f9d0bbf5ddaa4079b74bfb48475378b9
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06541638B2

Reaction notes

Loading…