HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Methylenedioxybenzyl-(3-azepin-1-yl-propyl)-amine → 1-Naphthylmethyl-[3-(3,5-difluorophenyl)-isoxazol-5-yl]-(3-azepin-1-yl-propyl)amine TFA salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Methylenedioxybenzyl-(3-azepin-1-yl-propyl)-amine | HCID 18612648 | — |
| Reactant | 3,4-Methylenedioxybenzyl-[3-(3,5-difluorophenyl)-isoxazol-5-yl](3-azepin-1-yl-propyl)-amine TFA salt | HCID 86758907 | — |
| Product | 1-Naphthylmethyl-[3-(3,5-difluorophenyl)-isoxazol-5-yl]-(3-azepin-1-yl-propyl)amine TFA salt | HCID 86758906 | — |
Reaction Steps
The title compound is prepared using a similar procedure as described for the preparation of 3,4-methylenedioxybenzyl-[3-(3,5-difluorophenyl)-isoxazol-5-yl]-(3-azepin-1-yl-propyl)-amine TFA salt (example 4) while substituting 1-Naphthylmethyl-(3-azepin-1-yl-propyl)-amine for 3,4-methylenedioxybenzyl-(3-azepin-1-yl-propyl)-amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544982B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-5ea2b0d885d249a182ff70b41b443b4e |
| Source note | uspto-grants-2003_04 |