HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-6-(1,3-dioxoisoindolin-2-yl)hexanoic Acid → 2-(4-(2-bromo-6-phthalimidohexanoyl-amino)-3-oxo-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl)-3-phenyl-propionic acid, N-methyl amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-6-(1,3-dioxoisoindolin-2-yl)hexanoic Acid | HCID 13622640 | — |
| Reactant | 2-(4-amino-3-oxo-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl)-3-phenyl-propionic acid, N-methyl amide | HCID 131723842 | — |
| Product | 2-(4-(2-bromo-6-phthalimidohexanoyl-amino)-3-oxo-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl)-3-phenyl-propionic acid, N-methyl amide | HCID 131723841 | — |
Reaction Steps
Prepare by the method of Example 3.1 using 2-(4-amino-3-oxo-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl)-3-phenyl-propionic acid, N-methyl amide and 2-bromo-6-phthalimidohexanoic acid to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544980B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-8a0810dd5e2842219b69caa5dfd84299 |
| Source note | uspto-grants-2003_04 |