HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-carbamoylbenzoate → Methyl 4-[4-[3,5-bis(trifluoromethyl)phenyl]-2-oxazolyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-carbamoylbenzoate | HCID 596094 | — |
| Reactant | 3,5-Bis(trifluoromethyl)phenacyl bromide | HCID 2736170 | — |
| Product | Methyl 4-[4-[3,5-bis(trifluoromethyl)phenyl]-2-oxazolyl]benzoate | HCID 18613896 | 24% |
Reaction Steps
In the same manner as in Example 1, methyl 4-carbamoylbenzoate was reacted with 3,5-bis(trifluoromethyl)phenacyl bromide to obtain methyl 4-[4-[3,5-bis(trifluoromethyl)phenyl]-2-oxazolyl]benzoate. The product was. recrystallized from ethanol., Yield: 24%. Pale yellow prisms. Melting Point: 180 to 181° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06545009B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-2492970650f54ecea2dfc14bd594a39b |
| Source note | uspto-grants-2003_04 |